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How is the DTaP/IPV/Hib vaccine different from the previous primary vaccinations?.

A The scientific teams that support the Department of Health are always reviewing the effect of immunizations and immunization programmes worldwide and constantly reviewing and making changes where necessary. A recent change includes the following:

The first immunizations your child has - the DTaP/IPV/Hib vaccine - has changed to the following:

  • The polio vaccine does not contain a live virus, so it no longer carries the slight risk of causing polio. The vaccine uses inactivated polio vaccine (IPV) instead of live oral vaccine. (OPV). Inactivated means that the viruses contained in the vaccine have been killed, so that they can't harm you.
  • The new vaccine causes fewer minor reactions
  • There is no thiomersal (mercury) in the vaccine, which could potentially have a small risk of producing allergic skin reactions
  • The vaccine uses acellular pertussis vaccine instead of whole-cell pertussis vaccine to protect babies against whooping cough.


    The changes were made to the vaccine because the global immunization programme against polio has been so effective in terms of reducing the risk of polio being brought into the UK. This means that it is now safe to change from a live oral vaccine (OPV) providing protection for the whole community to an inactivated polio vaccine (IPV) which provides effective individual protection. This inactivated polio vaccine does not carry carry any of the major risk associated with giving a live vaccine, such as the risk of the child or person having polio as a result of having the live vaccine.

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